Treatment of Locally Advanced or Inflammatory Breast Cancer

For information about the treatments listed below, see the Treatment Option Overview section.

Treatment of locally advanced or inflammatory breast cancer is a combination of therapies that may include:

• Surgery (breast-conserving surgery or total mastectomy) with lymph node dissection.
• Chemotherapy before and/or after surgery.
• Radiation therapy after surgery.
• Hormone therapy after surgery for tumors that are estrogen receptor positive or estrogen receptor unknown.
• Targeted therapy (trastuzumab and pertuzumab).
• Clinical trials testing new anticancer drugs, new drug combinations, and new ways of giving treatment.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.