Treatment of Stage III Renal Cell Cancer

For information about the treatments listed below, see the Treatment Option Overview section.

Treatment of stage III renal cell cancer may include the following:

• Surgery (radical nephrectomy).
• Arterial embolization followed by surgery (radical nephrectomy).
• Surgery (radical nephrectomy) followed by adjuvant therapy with pembrolizumab or sunitinib.
• Radiation therapy as palliative therapy to relieve symptoms and improve the quality of life.
• Arterial embolization as palliative therapy.
• Surgery (nephrectomy) as palliative therapy.
• Radiation therapy before or after surgery (radical nephrectomy).
• A clinical trial of immunotherapy following surgery.

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.